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April 21, 2021
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / April 21, 2021 ... Do hydrolyzed collagen supplements affect skin aging? DermWorld Insights and Inquiries : Nailing down the treatment for ungual melanoma in situ Young Physician Focus : A little
Histologic overreliance on mucin for diagnosis may prove…sticky
I am certain that I would have diagnosed tumid lupus in the patient presented by Gottesman et al – a 31 year-old man with edematous papules and nodules with histologic features demonstrating subtle vacuolar alteration at the epidermal-dermal junction, a superficial and deep perivascular and periadnexal lymphocytic infiltrate, and abundant
Supplement secrets unveiled: debunking common myths about beauty boosters
Board-certified dermatologist discusses what to consider before taking three common supplements ROSEMONT, Ill. (Sept. 17, 2024) — Nutritional supplements offer a convenient way to easily increase your daily intake of vitamins, minerals, and other nutrients without making significant lifestyle changes. Despite their growing popularity for achieving thicker hair and better
Supplements and the skin
Are nutritional supplements aimed at skin care helpful, harmful, or simply a placebo for patients? ... Feature ... By Heidi Splete, Contributing Writer, July 1, 2023 Nutritional supplements appeal to many individuals as an alternative or additive treatment for skin and hair ailments, but evidence to support the effectiveness of
January 28, 2026
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / Jan. 28, 2026 ... Topical estrogens for skin aging DermWorld What’s Hot: Driver of psoriatic itch Outcomes across JAK inhibitors in prurigo nodularis Anticholinergic treatments for hyperhidrosis Assessment of GPT-4 vision
What's hot?
What's hot ... May 29, 2018 In this monthly column, members of the ... Dermatology World Editorial Advisory Workgroup identify exciting news from across the specialty. ... Edward W. Cowen, MD, MHSc ... You may be surprised to learn that a ... new organ’ in the skin was recently identified.
Managing menopause
Dermatologists discuss dermatologic changes before and during menopause and the dermatoses that may occur. ... Feature ... By Allison Evans, Assistant Managing Editor, December 1, 2025 Menopausal transitions can be stressful. While rapidly declining estrogen levels can wreak havoc internally, many of these changes involve the skin, hair, and vulvar
The concept of atrophoderma of pasini and pierini as morphea may be falling off a cliff
Diagnosing Atrophoderma of Pasini and Pierini (APP) is reasonably straightforward – it usually presents in adolescents and young adults, more often in females, with sharply defined, single or multiple round to oval, hyperpigmented, depressed lesions with a “cliff-drop” border. Unusual presentations may include congenital lesions (1) or with a Blaschkoid
A string of (clinical) pearls about drug-induced linear IgA disease
The late sage Wallace Clark taught me that once a diagnosis is secured, thinking ceases. Admittedly in cases of drug-induced linear IgA dermatosis (DI-LAD) that I have encountered (due to vancomycin), once the diagnosis was suspected and confirmed, I never gave it too much thought. Recent findings in the DI-LAD
January 15, 2020
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / January 15, 2020 ... Which cosmeceuticals have proven clinical efficacy? DW Insights and Inquiries: Thoughts on hyaluronidase and The House of God Cancer death rate falls by largest one-year drop on
Vascular Ehlers-Danlos syndrome: From rupture to rapture?
Read the February 16, 2022 DermWorld Insights and Inquiries on Vascular Ehlers-Danlos syndrome.
Researching therapeutic reformation of the capillary malformation: Arteriovenous Malformation Syndrome
Read the June 17, 2020 DermWorld Insights and Inquiries on capillary malformation.
Striae due to bartonella is a stretch
I met a woman in her early 20’s who is being treated for chronic Lyme disease and Bartonella infections with multiple courses of antibiotics. During my examination, I noted several old white atrophic striae on her hip and leg. Her mother, who was accompanying her, stated matter-of-factly, “Those are due
Cannabinoids may elevate therapy for connective tissue diseases to a higher level
Medical “reefer madness” is taking hold in the United States with approximately 10% of cannabis users utilizing it for diverse medical conditions, including dermatologic disorders such as pruritus and atopic dermatitis. To date, at least 28 states allow for the use of medical cannabis. (1)
Taking it on the shin: Part one
This two-part commentary will focus on two disorders that involve the pretibial region — pretibial pruritic papular dermatitis (PPPD) and obesity-associated lymphedematous mucinosis (OALM).
Here’s looking at you, KID
Keratitis, ichthyosis, and deafness (KID) syndrome is a rare genodermatosis associated with mutations in the GJB2 gene, which encodes connexin 26. Abnormalities of this gap junction protein presumably affects epithelial differentiation, resulting in myriad clinical features.
1984: Dermatologically revisited
George Orwell published Nineteen Eighty-Four in 1949. I started my dermatopathology fellowship at the University of Pennsylvania in 1984. I decided to review Archives of Dermatology (now JAMA Dermatology), looking back 34 years to see how the dermatologic world has changed as depicted in a major dermatology journal.
How dry I am: The white scale sign of xerosis
When winter approaches my skin dries out. Fortunately, it doesn’t bother me at all. For others, especially in the elderly, xerosis be a predisposing factor for asteototic eczema, nummular dermatitis or dyshidrotic eczema.
Thyroid hormone, mitochondria, photoaging and April 7, 2017
On April 7, 1997 I filed a patent entitled “Method for the treatment of dry skin”, utilizing topical thyroid hormone. The publication date of the patent US5951989 was September 14, 1999. The expiration date is April 7, 2017.
Of sirolimus, shagreen, and chagrin
By the time I left the superlative World Congress of Pediatric Dermatology in Chicago I wanted to add sirolimus to the water supply. The indications for sirolimus include an expanding list of vascular/lymphatic malformations and manifestations of tuberous sclerosis (TS), thus offering a bright, non-surgical future for other previously recalcitrant
What's hot?
What's hot ... February 26, 2019 In this monthly column, members of the ... Dermatology World Editorial Advisory Workgroup identify exciting news from across the specialty. ... Mallory Abate, MD ... Isn’t it interesting how some common warts that we treat seem to go away almost instantly but others persist
OblIgEd to search for steroid-sparing agents in treating bullous pemphigoid
I’m always anxious to learn about alternative approaches for treating bullous pemphigoid (BP).
An encapsulation of palisaded encapsulated neuromas
Case reports and retrospective studies have demonstrated dupilumab’s efficacy in treating bullous pemphigoid. Preliminary data from a prospective trial confirms dupilumab’s therapeutic value. Perhaps approval of dupilumab for bullous pemphigoid is on the horizon.
The journey of focal dermal hypoplasia: From description to inspired therapy
The dermatologic community lost a giant in 2014 with the passing of Robert W. Goltz, MD at the age of 90. Dr. Goltz was not only responsible for describing focal dermal hypoplasia (FDH), but also multicentric reticulohistiocytosis, generalized elastolysis, and the nevoid basal cell carcinoma syndrome (with his good friend
Time for a Churchillian approach to idiopathic guttate hypomelanosis?
I lost my enthusiasm for treating idiopathic guttate hypomelanosis (IGH) long ago. Sir Winston would not have been proud. Perhaps it is time to reconsider some options for treating IGH.
Taking it on the shin: Part two
Obesity-associated lymphedematous mucinosis and stasis mucinosis can be differentiated from euthyroid pretibial myxedema. Weight reduction and compression may improve these disorders.
Studying skin aging never gets old: The potential role of oxytocin
Read the October 14, 2020 DermWorld Insights and Inquiries on oxytocin and aging skin.
Pineapple and cicatricial pemphigoid: A need to dole out more studies
The benefits of pineapples have been touted in folk medicine for years. Increasing knowledge of its active ingredient bromelain has lead to a therapeutic pineapple renaissance.
Tofacitinib for dermatomyositis: A potential belle of the ball?
JAK1/3 signaling participates in the pathogenesis of inflammatory disorders while JAK1/2 signaling plays a role in the development of several malignancies including leukemias, lymphomas, and myeloproliferative neoplasms. Tofacitinib (Xeljans) is a pan-JAK inhibitor that is approved by the FDA for the treatment of rheumatoid arthritis and ruxolitinib (Jakafi) is a
Stiff skin syndrome: Hard in many ways
Stiff skin syndrome (SSS) is a noninflammatory, fibrosing condition of the skin and fascia, often affecting the limb girdle region, notably the buttock and thighs, resulting in a lordotic posture.
Atrophic tinea versicolor: Knowledge about its pathogenesis is hypertrophying
In the entry “Atrophic Tinea Versicolor: More Than a Mirage” (April 22, 2016), I learned that the atrophic appearance of some cases of tinea versicolor is not just an optical illusion.
Lending a helping hand to our patients with Dupuytren’s disease
Read the Oct. 26, 2022 DermWorld Insights and Inquiries on Dupuytren’s disease.
Unrestricted fascination with restrictive dermopathy
Read the Nov. 16, 2022 DermWorld Insights and Inquiries on restrictive dermopathy.
The “rope” sign is knot pathognomonic: Autoimmunity ties the etiologies together
The “rope” sign is a dramatic finding presenting as a linear to curvilinear cords (“cordonifom”) on the lateral chest. It was originally described as an uncommon, but specific feature of Interstitial Granulomatous Dermatitis with Arthritis (IGDA), and has been considered pathognomonic for that disorder. That perspective is no longer tenable.
An appetite for healthy skin
Can diet affect dermatologic health? Experts weigh in on the evidence. ... Feature ... By Emily Margosian, assistant editor, November 1, 2020 You are what you eat — more than just a mantra, the phrase encapsulates a growing public desire for food-based solutions to targeted health outcomes. However, mixed media
From "slugging" to snail mucin
Dermatologists discuss popular social media trends impacting the skin. ... Feature ... By Emily Margosian, Assistant Editor, October 1, 2023 Social media and the skin have a long history together. For over 15 years, social media has been an ever-growing presence in nearly all facets of life: politics, commerce —
For the win! Championing the use of the term “reactive granulomatous dermatitis” in clinical practice
Read the March 8, 2023 DermWorld Insights and Inquiries on championing the use of the term “reactive granulomatous dermatitis” in clinical practice.
Necrobiosis lipoidica in a Wink
Read the May 3, 2023 DermWorld Insights and Inquiries on Necrobiosis lipoidica in a Wink. Necrobiosis lipoidica is usually associated with diabetes, but may also be accompanied by thyroid disease, hypertension, hyperlipidemia, and other disorders. JAK inhibitors are on the horizon in treating the granulomatous component of the disorder.
October 6, 2021
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / Oct. 6, 2021 ... A review of oral nail growth supplements DermWorld Insights and Inquiries : Granular detail on granular parakeratosis Coding guidance on reporting lesion services Implementation of COVID-19 phototherapy
April 15, 2026
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / April 15, 2026 ... Benefits, misconceptions, and risks of skin care supplements DermWorld What’s Hot: Using a RegiSCAR score to evaluate DRESS AAD seeks member comments for HS guidelines FDA approves
Of every possible solution for elastosis perforans serpiginosa, fractional carbon dioxide laser may be the best
My initial attraction to dermatology, which still offers great appeal, is the challenge and joy of differential diagnosis and clinical-pathologic correlation. I learned quickly, however, that patients don’t want to be interesting – they want a specific diagnosis for one reason only – to get the right treatment, preferably curative.
April 14, 2021
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / April 14, 2021 ... Pulsed dye laser versus ablative fractional CO2 laser for hypertrophic scars DermWorld Insights and Inquiries : LIDA rose the insulin requirement Actinic keratosis clinical guideline published Do
December 17, 2025
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / Dec. 17, 2025 ... Antiandrogen therapy for female pattern hair loss DermWorld Insights and Inquiries : Long COVID has a lot of nerve Hidradenitis suppurativa treatment during pregnancy, lactation The role
Platelet rich plasma: Good for whatever ails you?
Okay, okay, I admit it. The first time I ever heard of injecting autologous platelet rich plasma (PRP) for pattern alopecia, my suspicion was that it was being sold by the proverbial snake-oil salesman. I did my utmost to ignore it, but increasingly its use is being reported, and patients
Feeling stressed? It can show in your skin, hair, and nails
Board-certified dermatologist provides the latest information on how mind body practices can help skin and hair conditions VANCOUVER, BC. (July 21, 2022) — Stress is a part of life. Whether your stressors are small or large, they can impact both your mental and physical well-being. While we can’t completely remove
A new spin
Go to AAD Home ... Go to AAD Home ... Menu ... Examining the theory behind the use of platelet rich plasma for dermatologic procedures ... Examining the theory behind the use of platelet rich plasma for dermatologic procedures ... By Victoria Houghton, assistant managing editor Professional football players, world-renowned
A quiver full of fillers
Go to AAD Home ... Go to AAD Home ... Menu ... New approvals target specific anatomic locations ... New approvals target specific anatomic locations ... By Ruth Carol, contributing writer There has been an influx of dermal fillers approved by the Food and Drug Administration (FDA) in recent years.
January 11, 2023
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / Jan. 11, 2023 ... Antihistamines as adjunct therapy for alopecia areata DermWorld Insights and Inquiries : Acquisition and loss — A tribute to Jouni Uitto, MD, PhD Lidocaine shortage: Ask the
Is dyshidrosiform pemphigoid really anti-p200 pemphigoid?
Dyshidrosiform pemphigoid (DP) was initially reported in a 72 year-old man with large, tense bullae on the plantar aspect of his feet, with some lesions on an erythematous base. He also had an “ill-defined papular eruption” of the trunk and an erosion of the posterior pharynx. Routine microscopy demonstrated a
This month’s news from across the specialty
What’s hot ... December 1, 2024 In this monthly column, members of the ... DermWorld Editorial Advisory Workgroup identify exciting news from across the specialty. ... Craig Burkhart, MD, MS, MPH, FAAD More than 80% of prior authorization appeals are overturned. Insurance plans’ most common interventions to manage utilization
The many uses of microneedling
Go to AAD Home ... Go to AAD Home ... Menu ... How it works, potential applications, and what patients should know ... How it works, potential applications, and what patients should know ... By Emily Margosian, assistant editor Once an experimental treatment pioneered through the use of tattoo pistols
Your Dermatologist Knows media wins 2024
A key part of Your Dermatologist Knows is pitching stories to media outlets in hopes they’ll run news stories sharing information about the wide breadth of knowledge dermatologists have to their readership. We consider every new story published as a result of our pitches as a win, regardless of whether
December 14, 2022
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / Dec. 14, 2022 ... Are nutritional supplements effective for hair loss? DermWorld Insights and Inquiries : A Frank discussion about earlobe creases DermWorld Young Physician Focus : Zoonotic dermatoses – When
October 14, 2020
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / October 14, 2020 ... OTC scar treatments: What does the evidence say about efficacy? DermWorld Insights and Inquiries : Studying skin aging never gets old — The potential role of oxytocin
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... In the wake of the 40th anniversary of the onset of the HIV epidemic , DermWorld Weekly ... talks to Harold Brody, MD, FAAD, co-chair of the Board of Directors of another organization marking its
May 6, 2026
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / May 6, 2026 ... Nutritional, light-based, and lifestyle interventions for androgenetic alopecia DermWorld Insights and Inquiries : Granular C3 dermatosis in granular detail Risk of infection with JAK inhibitors Oral vs.
July 31, 2024
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / July 31, 2024 ... Does an increase in omega-3 fatty acids improve acne? DermWorld Insights and Inquiries : Which treatment modality of pyogenic granuloma is worth its weight in salt? Is
November 18, 2020
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / November 18, 2020 ... Hydrogen peroxide and the common wart: Phase 2 results are in DermWorld Insights and Inquiries : Granulomatous slack skin — More than one type of mimicry FDA
This month's news from across the specialty
What's hot ... February 1, 2021 In this monthly column, members of the ... DermWorld Editorial Advisory Workgroup identify exciting news from across the specialty. ... Craig Burkhart, MD, MPH, MSBS A ... recent blog in Medical Care reviews how health misinformation has been growing across internet and social
March 19, 2025
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / March 19, 2025 ... Association between actinic keratosis treatments and use of antihypertensives? DermWorld Insights and Inquiries : Mastering dermatology Laser and energy treatments for acne scarring Efficacy of upadacitinib vs.
Pregnant with possibility: Rituximab prophylaxis for pemphigoid gestationis
I was taken aback by the report of anhydramnios in two women with pemphigoid gestationis (PG) resulting in the death of the newborn babies within days of birth. Each child died of sepsis. (1)
From mentoring LGBT dermatologists, to caring for HIV patients, GALDA looks back on its 40-year journey
Answers in Practice ... By Victoria Houghton, Managing Editor, November 1, 2021 In the wake of the 40th anniversary of the onset of the HIV epidemic , DermWorld ... talks to Harold Brody, MD, FAAD, co-chair of the Board of Directors of another organization marking its 40th anniversary — the
This month’s news from across the specialty
What’s hot ... October 1, 2025 In this monthly column, members of the DermWorld ... Editorial Advisory Workgroup identify exciting news from across the specialty. Rosalie Elenitsas, MD, FAAD Pathologists and dermatopathologists frequently encounter poorly differentiated tumors that fail to reveal a defined lineage. In cutaneous specimens, these are
The H syndrome – Understanding Y
Read the April 15, 2020 DermWorld Insight and Inquiries on H syndrome.
Laser focus
Dermatologist experts discuss the latest advances in laser technology and offer tips on how to navigate the research and acquisition process ... Feature ... By Allison Evans, assistant managing editor, April 1, 2021 For the new dermatologist moving from residency to practice, or the established dermatologist simply seeking a challenge,
Aiming to hit the target in cutaneous granulomatous diseases
DermWorld discusses the latest treatment strategies for granulomatous skin diseases, and clinical advice for how to manage patients in the absence of approved therapies. ... Feature ... By Heidi Splete, Contributing Writer, February 1, 2026 Approved treatments for granulomatous skin diseases are lacking, but a growing number of case series
This month's news from across the specialty
What's hot ... March 1, 2020 In this monthly column, members of ... Dermatology World 's Editorial Advisory Workgroup identify exciting news from across the specialty. ... BRYAN CARROLL, MD, PHD There are relationships of psoriasis lesions with candida, staph aureus, and now bacteriophages. Our understanding of the interplay
What's hot?
What's hot ... December 30, 2017 In this monthly column, members of ... Dermatology World 's Editorial Advisory Workgroup identify exciting news from across the specialty. ... Annie Chiu, MD ... Body contouring is not only in demand among patients but presents a unique challenge for physicians to achieve consistent
Injecting ideas (and therapies) in digital mucous cysts
Digital mucous (myxoid) cysts are often associated with osteoarthritis. Multiple therapeutic maneuvers may be utilized, but the best results remain with surgical excision.
Beyond dermoscopy
Emergent technologies enhance imaging, target rare diseases. ... Feature ... By Jan Bowers, Contributing Writer, August 1, 2023 Dermoscopy has arrived. "While there are established practicing dermatologists who are not using it, it’s integrated across the residency programs," said Ashfaq A. Marghoob, MD, FAAD, attending physician at Memorial Sloan Kettering
Photobiomodulation: Seeing the light
DermWorld highlights the most popular (and effective) applications of red-light therapies, and how to advise patients about the proliferation of products for at-home use. ... Feature ... By Heidi Splete, Contributing Writer, December 1, 2025 Photobiomodulation (PBM) — including low-level laser therapy, low-light therapy, or red-light therapy — involves the
Vascular abnormalities in FFA, artificial intelligence, and Winston Churchill
Dilated, depressed frontal veins are a clinical sign of frontal fibrosing alopecia.
No longer flailing with Flegel disease
Read the April 19, 2023 DermWorld Insights and Inquiries on Flegel disease.
Appropriate use of skin substitutes in dermatology: Documentation and coding guidance
Derm Coding Consult ... By Faith C. M. McNicholas, RHIT, CPC, CPCD, PCS, CDC, Senior Manager, Coding and Reimbursement, August 1, 2025 Academy coding staff address important coding topics each month in DermWorld ... Coding Consult. Read more Derm Coding Consult articles . Skin substitutes are a diverse group of
Like the tumor itself, knowledge about DFSP is expanding wider and deeper
Read the June 16, 2021 DermWorld Insights and Inquiries on DFSP.
Can tocilizumab deep six recalcitrant morphea?
The IL-6 inhibitor tocilizumab may have a therapeutic role in cases of recalcitrant morphea.
Lipodystrophia semicircularis: A lipoatrophy not to get depressed about
Read the Nov. 2, 2022 DermWorld Insights and Inquiries on lipodystrophia semicircularis.
Recognizing toxic epidermal necrolysis-like acute cutaneous lupus erythematosus ASAP
Read the November 10, 2021 DermWorld Insights and Inquiries on recognizing toxic epidermal necrolysis-like acute cutaneous lupus erythematosus.
Acquisition and loss: A tribute to Jouni Uitto, MD, PhD
Read the Jan. 11, 2023 DermWorld Insights and Inquiries on acquisition and loss, a tribute to Jouni Uitto, MD, PhD.
A seasoned approach to treating the “salt and pepper” dyspigmentation of systemic sclerosis
Read the Feb. 1, 2023 DermWorld Insights and Inquiries on treating the “salt and pepper” dyspigmentation of systemic sclerosis.
Human papillomavirus 42: Putting a finger on the pathogenesis of digital papillary adenocarcinomas
DermWorld Insights and Inquiries ... By Warren R. Heymann, MD, FAAD, July 1, 2026 Vol. 8, No. 7 Lumps and bumps make me nervous, especially when presented as a "by the way, while I’m here, what do you think of this?" lesion. I’ll ask a few questions: "How long has
Cosmetic complications
Dermatologists offer insight and instruction for approaching procedural afflictions. ... Feature ... By Laura Vernaci, Contributing Writer, September 1, 2025 It goes without saying that dermatologists do everything in their power to keep their patients safe and avoid complications or adverse events. However, stay in the business long enough and
Dermatofibrosarcoma protuberans recurrence: Size matters
Dermatofibrosarcoma protuberans can be locally destructive and may rarely be fatal. Having the lesion excised (preferably with Mohs micrographic surgery) is the definitive foundation of treatment.
Getting physical
Go to AAD Home ... Go to AAD Home ... Menu ... Does a physician's relationship to fitness affect patient care? ... Does a physician's relationship to fitness affect patient care? ... By Allison Evans, assistant managing editor ... A physician’s job, pared down to its most simplistic form,
The role of GLP-1s in dermatology
Dermatologists discuss how the use of GLP-1s has offered potential new avenues for patients with chronic inflammatory skin diseases. ... Feature ... By Allison Evans, Assistant Managing Editor, January 1, 2026 Over the past five years, the approvals of glucagon-like peptide-1 receptor agonists (GLP-1s), particularly semaglutide and tirzepatide, have sparked
Dermatology World Weekly
An archive of issues of DermWorld Weekly.