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April 21, 2021
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / April 21, 2021 ... Do hydrolyzed collagen supplements affect skin aging? DermWorld Insights and Inquiries : Nailing down the treatment for ungual melanoma in situ Young Physician Focus : A little
Supplements and the skin
Are nutritional supplements aimed at skin care helpful, harmful, or simply a placebo for patients? ... Feature ... By Heidi Splete, Contributing Writer, July 1, 2023 Nutritional supplements appeal to many individuals as an alternative or additive treatment for skin and hair ailments, but evidence to support the effectiveness of
How dry I am: The white scale sign of xerosis
By Warren R. Heymann, MD Dec. 22, 2016 When winter approaches my skin dries out. Fortunately, it doesn’t bother me at all. For others, especially in the elderly, xerosis be a predisposing factor for asteototic eczema, nummular dermatitis or dyshidrotic eczema (1). With so many people presenting with dry
What's hot?
What's hot ... May 29, 2018 In this monthly column, members of the ... Dermatology World Editorial Advisory Workgroup identify exciting news from across the specialty. ... Edward W. Cowen, MD, MHSc ... You may be surprised to learn that a ... new organ’ in the skin was recently identified.
Of sirolimus, shagreen, and chagrin
By Warren R. Heymann, MD July 24, 2017 Shagreen patch is a connective tissue hamartoma composed of excess collagen and elastic tissue. ... Credit: ... JAAD By the time I left the superlative World Congress of Pediatric Dermatology in Chicago I wanted to add sirolimus to the water supply. The
Studying skin aging never gets old: The potential role of oxytocin
By Warren R. Heymann, MD Oct. 14, 2020 Vol. 2, No. 41 Every day, dermatologists address patient concerns about their aging skin — whether they are presenting for medical, surgical, or cosmetic problems. Extrinsic factors such as ultraviolet light and smoking resulting in a leathery, coarsely wrinkled appearance are well
Tofacitinib for dermatomyositis: A potential belle of the ball?
By Warren R. Heymann, MD Aug. 23, 2016 JAK1/3 signaling participates in the pathogenesis of inflammatory disorders while JAK1/2 signaling plays a role in the development of several malignancies including leukemias, lymphomas, and myeloproliferative neoplasms. Tofacitinib (Xeljans) is a pan-JAK inhibitor that is approved by the FDA for the treatment
Develop a nose for suspecting angiosarcoma
Angiosarcoma histopathology. Anastomosing dilated vessels, lined by crowded endothelial cells, extend between pre-existing collagen bundles. (Hematoxylin-eosin-saffron stain; original magnification: ×40.) ... Credit: ... JAAD By Warren R. Heymann, MD Nov. 12, 2018 Occasionally I read an article that disturbs me, because I know that I would miss the diagnosis, with
PDF of Cosmoceuticals
lightening retinol, retinoic of matrix metalloproteinases cells in the skin acid, provitamin reduces collagen
Wound healing biology
Fibroblasts: Make ECM Fibroblasts migrate via fibronectin matrix to deposit collagen, proteoglycans
The concept of atrophoderma of pasini and pierini as morphea may be falling off a cliff
By Warren R. Heymann, MD Nov. 6, 2017 ... Clinical photos of idiopathic atrophoderma of Pierini and Pasini. ... Credit: ... JAAD Diagnosing Atrophoderma of Pasini and Pierini (APP) is reasonably straightforward — it usually presents in adolescents and young adults, more often in females, with sharply defined, single or
Histologic overreliance on mucin for diagnosis may prove…sticky
By Warren R. Heymann, MD July 27, 2017 Cutaneous lupus mucinosis. A, Before treatment, large nodules covered with erythematous skin are seen on the lower back. B, After treatment with systemic prednisolone and tacrolimus, the sizes of the nodules are decreased and pigmentation is observed on the surface of the
PDF of Retinoid biology part 2
) Cosmeceuticals Vitamin C L-ascorbic acid is the predominant antioxidant in the skin Essential for collagen
A string of (clinical) pearls about drug-induced linear IgA disease
By Warren R. Heymann, MD Aug. 6, 2018 Linear IgA dermatosis patient with urticarial eruption of the trunk. ... Credit: ... JAAD The late sage Wallace Clark taught me that once a diagnosis is secured, thinking ceases. Admittedly in cases of drug-induced linear IgA dermatosis (DI-LAD) that I have encountered
January 15, 2020
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / January 15, 2020 ... Which cosmeceuticals have proven clinical efficacy? DW Insights and Inquiries: Thoughts on hyaluronidase and The House of God Cancer death rate falls by largest one-year drop on
Vascular Ehlers-Danlos syndrome: From rupture to rapture?
By Warren R. Heymann, MD, FAAD February 16, 2022 Vol. 4, No. 7 If there was a statistic for a dermatological diagnostic impact factor, vascular Ehlers-Danlos syndrome (vEDS) would be at the top. Often undiagnosed until tragedy strikes, astute dermatologists who consider the diagnosis prior to an acute event may
PDF of Dermatopathologic external agents and artifacts
infectious process effaced with horizontal fibrosis, leishmaniasis) if needed vertical vessels, and collagen
Researching therapeutic reformation of the capillary malformation: Arteriovenous Malformation Syndrome
By Warren R. Heymann, MD June 17, 2020 Vol. 2, No. 24 Small cutaneous lesions may have profound systemic implications. Astute dermatologists will recognize these lesions and assess patients accordingly, often to the surprise of referring physicians and patients alike. ... The Capillary Malformation – Arteriovenous Malformation (CM-AVM) syndrome was
PDF of Soft tissue fillers, part 1: Biodegradable
Source Trade Name Autologous human collagen Autologen® Non-cadaveric human collagen CosmoDerm® 1, CosmoDerm
PDF of biodegradeable part 1
Source Trade Name Autologous human collagen Autologen® Non-cadaveric human collagen CosmoDerm® 1, CosmoDerm
Striae due to bartonella is a stretch
By Warren R. Heymann, MD May 1, 2018 ... A, Localized striae distensae on the left upper limb (flexor aspect). B, Clinical improvement 9 weeks after treatment. ... Credit: ... JAAD I met a woman in her early 20’s who is being treated for chronic Lyme disease and Bartonella infections
Cannabinoids may elevate therapy for connective tissue diseases to a higher level
By Warren R. Heymann, MD Nov. 2, 2017 Medical "reefer madness" is taking hold in the United States with approximately 10% of cannabis users utilizing it for diverse medical conditions, including dermatologic disorders such as pruritus and atopic dermatitis. To date, at least 28 states allow for the use of
PDF of Boards Fodder Non-surgical scar revision
Imiquimod IFN-α induces Variable, as 5% cream, 12 Nightly for eight Skin the American College • Cream collagen
PDF of bullous disease
Laminin 5- a3 conjunctiva most base, rupture EOS, PMNs LAD1, a6b4 common; easily Esophageal, Type VII collagen
PDF of cosmetic career case study
That more than 20 years for collagen at Stanford, so I had an early exposure to opportunity was not
PDF of Epidermolysis Bullosa
melanocytic nevi non-Herlitz Type XVII improve with age; milia; scar- Dental pitting/caries generalized collagen
Taking it on the shin: Part one
By Warren R. Heymann, MD, FAAD May 31, 2023 Vol. 5, No. 22 I am intentionally skeptical of medical literature that purports "new" entities. Are they novel and distinct or just minor variations of long-recognized dermatoses? This two-part commentary will focus on two disorders that involve the pretibial region —
PDF of Genes
FGF RECEPTOR 2 Bannayan-Riley-Ruvalcaba AD PTEN Tumor Suppressor Bart’s Syndrome AD (COL7A1) TYPE VII COLLAGEN
Here’s looking at you, KID
By Warren R. Heymann, MD April 7, 2017 Late skin findings in lethal keratitis-ichthyosis-deafness syndrome. Intertriginous hyperkeratosis and denudation in a patient with GJB2 p.A88V mutation. ... Credit: ... JAAD Keratitis, ichthyosis, and deafness (KID) syndrome is a rare genodermatosis associated with mutations in the GJB2 gene, which encodes connexin
1984: Dermatologically revisited
By Warren R. Heymann, MD Aug. 22, 2018 George Orwell published ... Nineteen Eighty-Four in 1949. I started my dermatopathology fellowship at the University of Pennsylvania in 1984. I decided to review ... Archives of Dermatology (now ... JAMA Dermatology ), looking back 34 years to see how the dermatologic
Thyroid hormone, mitochondria, photoaging and April 7, 2017
By Warren R. Heymann, MD Sept. 24, 2016 On April 7, 1997 I filed a patent entitled "Method for the treatment of dry skin," utilizing topical thyroid hormone. The publication date of the patent US5951989 was September 14, 1999. The expiration date is April 7, 2017. ... Some of you
What's hot?
What's hot ... February 26, 2019 In this monthly column, members of the ... Dermatology World Editorial Advisory Workgroup identify exciting news from across the specialty. ... Mallory Abate, MD ... Isn’t it interesting how some common warts that we treat seem to go away almost instantly but others persist
OblIgEd to search for steroid-sparing agents in treating bullous pemphigoid
By Warren R. Heymann, MD ... Jan. 19, 2017 ... I’m always anxious to learn about alternative approaches for treating bullous pemphigoid (BP). Perhaps it’s my imagination, but most of my patients with BP are elderly, diabetic, hypertensive, and anticoagulated. It is impossible to prescribe rituximab out of the
PDF of Direct immunofluorescence patterns
malignancy (25%); IgA (20%); IgM Ocular subtype: beta-4-integrin Non -Pemphigoid Epidermolysis Bullosa Collagen
PDF of Granulomas
lymphocytes around racial predilection; Th1-type inflam- Generalized: 10-100s small tors central altered collagen
Time for a Churchillian approach to idiopathic guttate hypomelanosis?
By Warren R. Heymann, MD Jan. 22, 2018 Limbs of patient with idiopathic guttate hypomelanosis lesions. ... Credit: ... JAAD I was only 10 years old when Winston Churchill died, but even as a child I was aware of his inspirational abilities. I was reminded his gift watching Gary
The journey of focal dermal hypoplasia: From description to inspired therapy
By Warren R. Heymann, MD Oct. 9, 2017 The dermatologic community lost a giant in 2014 with the passing of Robert W. Goltz, MD at the age of 90. Dr. Goltz was not only responsible for describing focal dermal hypoplasia (FDH), but also multicentric reticulohistiocytosis, generalized elastolysis, and the nevoid
Taking it on the shin: Part two
By Warren R. Heymann, MD, FAAD June 7, 2023 Vol. 5, No. 23 Last week ... pretibial pruritic papular dermatitis was reviewed as an underrecognized entity on the shins. Today the focus is on obesity-associated lymphedematous mucinosis (OALM), another disorder that you have likely seen, but perhaps did not recognize.
Pineapple and cicatricial pemphigoid: A need to dole out more studies
By Warren R. Heymann, MD Oct. 4, 2016 The benefits of pineapples have been touted in folk medicine for years. Increasing knowledge of its active ingredient bromelain has lead to a therapeutic pineapple renaissance. Bromelain is a complex natural mixture of proteolytic enzymes derived from pineapple (Ananas cosmosus) and possesses
PDF of Paisley Tie Diagnosis
on pattern. the cheek of a young • Horn cysts with cal- woman. cification common • Clefts between collagen
Stiff skin syndrome: Hard in many ways
By Warren R. Heymann, MD July 4, 2016 Stiff skin syndrome (SSS) is a noninflammatory, fibrosing condition of the skin and fascia, often affecting the limb girdle region, notably the buttock and thighs, resulting in a lordotic posture. It may be accompanied by subtle hypertrichosis and hyperpigmentation. The course tends
PDF of summer 2021 DIR
infectious process effaced with horizontal fibrosis, leishmaniasis) if needed vertical vessels, and collagen
Atrophic tinea versicolor: Knowledge about its pathogenesis is hypertrophying
By Warren R. Heymann, MD April 12, 2017 In the entry "Atrophic Tinea Versicolor: More Than a Mirage" (April 22, 2016), I learned that the atrophic appearance of some cases of tinea versicolor is not just an optical illusion. The case of a 35-year-old man with depressed brown lesions on
Microneedling: experienced hands can improve the face
SAN DIEGO (Feb. 16, 2018) — Treatment from a trained doctor provides better results than at-home devices When it comes to microneedling, not all treatments are created equal. At-home devices won’t provide the same effects as an in-office treatment from a board-certified dermatologist. ... "Microneedling that delivers significant, long-lasting
Unrestricted fascination with restrictive dermopathy
By Warren R. Heymann, MD, FAAD Nov. 16, 2022 Vol. 4, No. 46 Barely a week into our fellowships at the University of Pennsylvania in 1984, my wife (a geneticist) asked her favorite dermatologist (me) if I had any thoughts about a neonate with skin that was thin, taut, and
Lending a helping hand to our patients with Dupuytren’s disease
By Warren R. Heymann, MD, FAAD Oct. 26, 2022 Vol. 4, No. 43 When patients trust you, they want your opinion, even if the disorder in question is out of your bailiwick. Although likely to refer patients with Dupuytren’s disease (DD, aka Dupuytren’s contracture, DC) directly to an orthopedic (hand)
PDF of Retinoid biology, part 1
differentiation, increased keratohyaline granules, Odland body secretion, increased fillagrin Increased collagen
The “rope” sign is knot pathognomonic: Autoimmunity ties the etiologies together
By Warren R. Heymann, MD July 8, 2016 The "rope" sign is a dramatic finding presenting as a linear to curvilinear cords ("cordonifom") on the lateral chest. It was originally described as an uncommon, but specific feature of Interstitial Granulomatous Dermatitis with Arthritis (IGDA), and has been considered pathognomonic for
From "slugging" to snail mucin
Dermatologists discuss popular social media trends impacting the skin. ... Feature ... By Emily Margosian, Assistant Editor, October 1, 2023 Social media and the skin have a long history together. For over 15 years, social media has been an ever-growing presence in nearly all facets of life: politics, commerce —
An appetite for healthy skin
Can diet affect dermatologic health? Experts weigh in on the evidence. ... Feature ... By Emily Margosian, assistant editor, November 1, 2020 You are what you eat — more than just a mantra, the phrase encapsulates a growing public desire for food-based solutions to targeted health outcomes. However, mixed media
Necrobiosis lipoidica in a Wink
By Warren R. Heymann, MD, FAAD May 3, 2023 Vol. 5, No. 18 Ninety years have transpired since Urbach coined the term ... necrobiosis lipoidica diabeticorum (NLD) for the granulomatous disorder first described by Oppenheim in 1929 as ... dermatitis atrophicans lipoidica diabetica . (1) Early authors observed sclerotic plaques
For the win! Championing the use of the term “reactive granulomatous dermatitis” in clinical practice
By David A. Wetter, MD, FAAD March 8, 2023 Vol. 5, No. 10 Growing up in the 1980s in suburban St. Louis, Missouri, I spent many evenings listening to Cardinals’ baseball on the local AM radio station, KMOX 1120. After the final out of each Cardinals’ victory, the late Hall-of-Fame
PDF of Histologic bodies
granules Well’s syndrome, Arthropod bites, other surrounding central masses of brightly pink amorphous collagen
October 6, 2021
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / Oct. 6, 2021 ... A review of oral nail growth supplements DermWorld Insights and Inquiries : Granular detail on granular parakeratosis Coding guidance on reporting lesion services Implementation of COVID-19 phototherapy
Of every possible solution for elastosis perforans serpiginosa, fractional carbon dioxide laser may be the best
By Warren R. Heymann, MD Nov. 13, 2017 ... Elastosis perforans serpiginosa. Clinical presentation. ... Credit: ... JAAD My initial attraction to dermatology, which still offers great appeal, is the challenge and joy of differential diagnosis and clinical-pathologic correlation. I learned quickly, however, that patients don’t want to be interesting
PDF of Lasers
cheilitis, verrucae, Cornea rhinophyma Pulsed Ablative skin resurfacing, Postoperative erythema Cornea collagen
PDF of Herbal supplements in dermatology
Promotes collagen Stinging, erythema, xerosis synthesis Antioxidant used for atopic dermatitis Vitamin
April 14, 2021
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / April 14, 2021 ... Pulsed dye laser versus ablative fractional CO2 laser for hypertrophic scars DermWorld Insights and Inquiries : LIDA rose the insulin requirement Actinic keratosis clinical guideline published Do
Platelet rich plasma: Good for whatever ails you?
By Warren R. Heymann, MD Jan. 13, 2017 Hair regrowth in ophiasis-type alopecia areata after platelet-rich plasma (PRP) injection. Occipital hair loss before treatment (A) and occipital hair regrowth 3 months after administration of PRP at a concentration 3.5 times above baseline (B). ... Credit: ... JAAD Okay, okay, I
Feeling stressed? It can show in your skin, hair, and nails
Board-certified dermatologist provides the latest information on how mind body practices can help skin and hair conditions VANCOUVER, BC. (July 21, 2022) — Stress is a part of life. Whether your stressors are small or large, they can impact both your mental and physical well-being. While we can’t completely remove
A new spin
Go to AAD Home ... Go to AAD Home ... Menu ... Examining the theory behind the use of platelet rich plasma for dermatologic procedures ... Examining the theory behind the use of platelet rich plasma for dermatologic procedures ... By Victoria Houghton, assistant managing editor Professional football players, world-renowned
A quiver full of fillers
Go to AAD Home ... Go to AAD Home ... Menu ... New approvals target specific anatomic locations ... New approvals target specific anatomic locations ... By Ruth Carol, contributing writer There has been an influx of dermal fillers approved by the Food and Drug Administration (FDA) in recent years.
January 11, 2023
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / Jan. 11, 2023 ... Antihistamines as adjunct therapy for alopecia areata DermWorld Insights and Inquiries : Acquisition and loss — A tribute to Jouni Uitto, MD, PhD Lidocaine shortage: Ask the
Is dyshidrosiform pemphigoid really anti-p200 pemphigoid?
By Warren R. Heymann, MD Aug. 20, 2016 Dyshidrosiform pemphigoid (DP) was initially reported in a 72 year-old man with large, tense bullae on the plantar aspect of his feet, with some lesions on an erythematous base. He also had an "ill-defined papular eruption" of the trunk and an erosion
This month's news from across the specialty
What's hot ... February 1, 2021 In this monthly column, members of the ... DermWorld Editorial Advisory Workgroup identify exciting news from across the specialty. ... Craig Burkhart, MD, MPH, MSBS A ... recent blog in Medical Care reviews how health misinformation has been growing across internet and social
The many uses of microneedling
Go to AAD Home ... Go to AAD Home ... Menu ... How it works, potential applications, and what patients should know ... How it works, potential applications, and what patients should know ... By Emily Margosian, assistant editor Once an experimental treatment pioneered through the use of tattoo pistols
PDF of Wound dressings
Chronic ulcers Xenograft Composed of bovine Donor sites Immediate availability Expensive or porcine collagen
PDF of Soft tissue fillers, non-biodegradable pt 2
Curcio, suspended in 3.5% dena- MD, MPH, originally tured bovine collagen, + published in 2011. 0.3%
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... In the wake of the 40th anniversary of the onset of the HIV epidemic , DermWorld Weekly ... talks to Harold Brody, MD, FAAD, co-chair of the Board of Directors of another organization marking its
December 14, 2022
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / Dec. 14, 2022 ... Are nutritional supplements effective for hair loss? DermWorld Insights and Inquiries : A Frank discussion about earlobe creases DermWorld Young Physician Focus : Zoonotic dermatoses – When
November 18, 2020
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / November 18, 2020 ... Hydrogen peroxide and the common wart: Phase 2 results are in DermWorld Insights and Inquiries : Granulomatous slack skin — More than one type of mimicry FDA
October 14, 2020
Derm World Weekly - A Publication of the American Academy of Dermatology | Association ... IN THIS ISSUE / October 14, 2020 ... OTC scar treatments: What does the evidence say about efficacy? DermWorld Insights and Inquiries : Studying skin aging never gets old — The potential role of oxytocin
From mentoring LGBT dermatologists, to caring for HIV patients, GALDA looks back on its 40-year journey
Answers in Practice ... By Victoria Houghton, Managing Editor, November 1, 2021 In the wake of the 40th anniversary of the onset of the HIV epidemic , DermWorld ... talks to Harold Brody, MD, FAAD, co-chair of the Board of Directors of another organization marking its 40th anniversary — the
PDF of Teeth
keratosis, wrinkling of hands / feet, phimosis, pseudoainhum Recessive dystrophic epidermolysis bullosa Collagen
The H syndrome – Understanding Y
By Warren R. Heymann, MD April 15, 2020 Vol. 2, No. 15 It has been more than a decade since the H syndrome was described by Molho-Pessach et al, in their report of 10 patients from 6 Arab consanguineous families. (1) More than 100 cases have now been reported worldwide.
Pregnant with possibility: Rituximab prophylaxis for pemphigoid gestationis
By Warren R. Heymann, MD April 26, 2018 ... Pemphigoid gestationis in 34-year-old primigravida at 28 weeks gestation. A, Urticated erythema with multiple tense blisters on both thighs. B, Histopathologic findings reveal subepidermal blister formation with abundant eosinophils, accompanied by superficial and middermal perivascular lymphohistiocytic infiltrate. (Hematoxylin-eosin stain; original magnification:
What's hot?
What's hot ... December 30, 2017 In this monthly column, members of ... Dermatology World 's Editorial Advisory Workgroup identify exciting news from across the specialty. ... Annie Chiu, MD ... Body contouring is not only in demand among patients but presents a unique challenge for physicians to achieve consistent
This month's news from across the specialty
What's hot ... March 1, 2020 In this monthly column, members of ... Dermatology World 's Editorial Advisory Workgroup identify exciting news from across the specialty. ... BRYAN CARROLL, MD, PHD There are relationships of psoriasis lesions with candida, staph aureus, and now bacteriophages. Our understanding of the interplay
Beyond dermoscopy
Emergent technologies enhance imaging, target rare diseases. ... Feature ... By Jan Bowers, Contributing Writer, August 1, 2023 Dermoscopy has arrived. "While there are established practicing dermatologists who are not using it, it’s integrated across the residency programs," said Ashfaq A. Marghoob, MD, FAAD, attending physician at Memorial Sloan Kettering
Laser focus
Dermatologist experts discuss the latest advances in laser technology and offer tips on how to navigate the research and acquisition process ... Feature ... By Allison Evans, assistant managing editor, April 1, 2021 For the new dermatologist moving from residency to practice, or the established dermatologist simply seeking a challenge,
PDF of Chemotherapy specific cutaneous reactions
cycle resulting Lower extremity foot ulcers in basal keratinocyte damage and Hydroxyurea hindered collagen
PDF of Panniculitis
hepatic cells splayed between weekly IV infusion. plaques with occa- fibrosis with eventual cirrhosis, collagen
PDF of Immunodeficiencies
B-cell as it develops or transfusions into IgA-producing • Asthma, autoimmunity (increase plasma cell collagen
Vascular abnormalities in FFA, artificial intelligence, and Winston Churchill
By Warren R. Heymann, MD, FAAD Aug. 23, 2023 Vol. 5, No. 34 If Winston Churchill were a dermatologist, he would say that frontal fibrosing alopecia (FFA) is "a riddle wrapped in a mystery inside an enigma" (which is how he viewed Russia). Almost 30 years have passed since Kossard
No longer flailing with Flegel disease
By Warren R. Heymann, MD, FAAD April 19, 2023 Vol. 5, No. 16 I was a toddler in 1958 when Heinz Flegel described ... hyperkeratosis lenticularis perstans (HLP) a 50-year-old man with persistent lesions on his dorsal feet and lower extremities. (1) In the ensuing decades, other than the clinical
PDF of Boards Fodder for Dermoscopic structures and their histopathological and clinical correlations
Histopathologic find- Clinical Image structure ings correlates Regression Blue-gray areas and Thickened collagen
PDF of Important immunohistochemical stains in dermatology
fibroxanthoma Vimentin+ CD68+ (57-62%) CD99+ α1 anti-trypsin and α1 anti-chymo- CD10+ trypsin + in >50% Pro-collagen
PDF of Oral disease, part 1
increased amount of drug or substitution with another Hyperplasia areas usually spared, but can involve collagen
PDF of Soundalikes in dermatology
Bart’s syndrome AD; collagen VII mutation; aplasia cutis congenita of the lower extremities, plus dominant
Like the tumor itself, knowledge about DFSP is expanding wider and deeper
By Warren Heymann, MD June 16, 2021 Vol. 3, No. 24 Dermatofibosarcoma (DFSP) is a mystifying lesion. Although considered rare, I have encountered several cases over the years. Some recent literature offers potential insights into its pathogenesis and management. ... DFSP is a low-to-intermediate grade sarcoma with a reported incidence
Can tocilizumab deep six recalcitrant morphea?
By Warren R. Heymann, MD, FAAD Sept. 20, 2023 Vol. 5, No. 38 Glenda’s middle-aged ankles still hurt badly. I have been treating morphea enveloping her ankles for several years. With therapies including methotrexate, mycophenolate mofetil, clobetasol, calcipotriene, and physical therapy, her tenderness has improved from exquisite to barely tolerable.
Lipodystrophia semicircularis: A lipoatrophy not to get depressed about
By Warren R. Heymann, MD, FAAD Nov. 2, 2022 Vol. 4, No. 44 A colleague asked me if I could evaluate his 26-year-old daughter while she was briefly on break from her graduate studies in Barcelona. He was concerned that she had developed lipodystrophy. Of course, I agreed, without his
Recognizing toxic epidermal necrolysis-like acute cutaneous lupus erythematosus ASAP
By Warren R. Heymann, MD, FAAD November 10, 2021 Vol. 3, No. 45 ASAP, the well-recognized acronym for "as soon as possible," takes on special significance for dermatologists confirming the diagnosis of toxic epidermal necrolysis (TEN). In 2004, Ting et al introduced an alternative definition of the ASAP acronym —
Acquisition and loss: A tribute to Jouni Uitto, MD, PhD
By Warren R. Heymann, MD, FAAD Jan. 11, 2023 Vol. 5, No. 2 I was stunned and frozen in time and thought when Dr. Sylvia Hsu informed me that Dr. Jouni Uitto had passed away — a similar reaction as I experienced when hearing of President Kennedy’s or John Lennon’s
A seasoned approach to treating the “salt and pepper” dyspigmentation of systemic sclerosis
By Warren R. Heymann, MD, FAAD Feb. 1, 2023 Vol. 5, No. 5 It only takes a nanosecond for a dermatologist to recognize the "salt and pepper" dyspigmentation (SPD) of systemic sclerosis (SSc), but a lifetime to understand and manage it. Of all the cutaneous signs of SSc (sclerodactyly, telangiectasias,
PDF of Bones, eyes, nails
related protein 1 Osteogenesis Imperfecta AD: genes encode type I Fragile bones (fractures) Blue sclera collagen
Dermatofibrosarcoma protuberans recurrence: Size matters
By Warren R. Heymann, MD, FAAD April 24, 2024 Vol. 6, No. 17 Editor’s note: An abridged version of this commentary was published in the November 2023 issue of the Journal of the American Academy of Dermatology ... . Dermatofibrosarcoma protuberans (DFSP) is a fascinating soft tissue tumor; although considered
Getting physical
Go to AAD Home ... Go to AAD Home ... Menu ... Does a physician's relationship to fitness affect patient care? ... Does a physician's relationship to fitness affect patient care? ... By Allison Evans, assistant managing editor ... A physician’s job, pared down to its most simplistic form,
PDF of gross and micro abstract programs
Diagnosis: DDA is a rare, acquired, reactive proliferation of vascular channels between collagen bundles
PDF of late-breaking research abstracts
incurable and fatal inherited blistering skin diseases due to mutations in the genes encoding type VII collagen
World Congress Fund Poster Abstract eBook
Skin thickness, collagen content, inltfi rating inflammatory with rashes on the nose and scalp.
PDF of resident & fellows abstract
Improved in vitro and in vivo collagen biosynthesis by asiaticoside-loaded ultradeformable vesicles.
Dermatology World Weekly
DermWorld Weekly is a brief, concise digest of the latest news, hand-picked by ... DW’s editorial team with analysis of why it matters to dermatologists. ... Each week editors review the landscape of health care news in ... DermWorld's core areas of practice management, policy, and patient care, and highlight